Subpial transection surgery for epilepsy

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چکیده

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Multiple subpial transection: a review of 21 cases.

Multiple subpial transection (MST) is a novel technique in surgery for epilepsy, employed in patients where some or all of the epileptogenic zone cannot be resected because it lies in a vital cortical area. Twenty one patients subjected to MST were reviewed. Eighteen patients had medically intractable epilepsy and three patients had Landau-Kleffner syndrome. Their ages ranged from 6 to 47 (mean...

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Treatment of refractory partial status epilepticus with multiple subpial transection: case report

Status epilepticus (SE) represents a medical emergency that annually affects 60,000--150,000 individuals in the United States. Selective neuronal loss in vulnerable areas has been pathologically demonstrated following convulsive SE primarily affecting the limbic system, thalamus and cerebellum. Morbidity in those cases that follow refractory SE (RSE) is poorly documented. There have been anecdo...

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Effect of multiple subpial transection on motor cortical excitability in cortical dysgenesis.

We report here a 12-year-old patient with unilateral cortical dysgenesis and intractable simple partial seizure in his left arm, who underwent multiple subpial transection (MST) in the right cerebral cortex including the primary motor cortex. We investigated motor cortical excitability using multimodal transcranial magnetic stimulation (TMS) before and 1 month after MST, in which surgical corti...

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Comment on outcome following multiple subpial transection in Landau-Kleffner syndrome and related regression.

OBJECTIVE To determine whether multiple subpial transection in the posterior temporal lobe has an impact on long-term outcome in children who have drug-resistant Landau-Kleffner syndrome (LKS) or other "electrical status epilepticus during sleep" (ESES)-related regression. Given the wide variability in outcomes reported in the literature, a secondary aim was to explore predictors of outcome. ...

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Surgery for epilepsy

While medical treatment remains the first line of treatment for epilepsy, surgery provides effective long-term control in suitable patients. Detailed investigations are necessary to prove suitability and in order to choose the appropriate procedure. This article gives an outline of the investigative programme and the various operative approaches. Novel methods and those under investigation are ...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2018

ISSN: 1465-1858

DOI: 10.1002/14651858.cd008153.pub4